منابع مشابه
Quantitative genetics of disease traits.
John James authored two key papers on the theory of risk to relatives for binary disease traits and the relationship between parameters on the observed binary scale and an unobserved scale of liability (James Annals of Human Genetics, 1971; 35: 47; Reich, James and Morris Annals of Human Genetics, 1972; 36: 163). These two papers are John James' most cited papers (198 and 328 citations, Novembe...
متن کاملQuantitative Genetics and Quantitative Traits
Introduction In the chapter on Mendel and Morgan, we saw how the transmission of genes from one generation to another follows precise mathematical formula. The traits discussed in that chapter, however, were discrete traits—peas are either yellow or green, someone either has a disorder or does not have the disorder. But many behavioral traits are not like these clear-cut, have-it-or-don’t-have-...
متن کاملMuscling in on the genetics of quantitative disease traits.
OUR COMPREHENSION of how genetic factors influence a person’s susceptibility to complex disease has evolved markedly during the past 20 years. Major advances in molecular genetics technologies have contributed greatly to this process, as have improvements in phenotyping methods and statistical algorithms used in the analysis of quantitative genetics data. Although genetics studies that focus on...
متن کاملStatistical Genetics and Evolution of Quantitative Traits
The distribution and heritability of many traits depends on numerous loci in the genome. In general, the astronomical number of possible genotypes makes the system with large numbers of loci difficult to describe. Multilocus evolution, however, greatly simplifies in the limit of weak selection and frequent recombination. In this limit, populations rapidly reach Quasi-Linkage Equilibrium (QLE) i...
متن کاملGenetics of quantitative and qualitative traits of isabgol (Plantago ovata).
Isabgol is a medicinal plant known for its high-quality dietary fiber. The genetics and inheritance of economic characters, such as number of panicles, panicle length, seed yield, and swelling factor, were measured by diallel analysis of F(1) progenies from seven parents. The additive component of genetic variance was significant for days to flowering, plant height, branches/plant, peduncle len...
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ژورنال
عنوان ژورنال: Journal of Animal Breeding and Genetics
سال: 2015
ISSN: 0931-2668
DOI: 10.1111/jbg.12153